Clinical & Research

Scientific pitch

Unintended pregnancies cost 11 billion each year in the US [1]. The IUD is regarded as the most cost-effective reversible contraceptive solution [2,3,4]. However, fear of pain or reported severe pain at the IUD placement remains an acceptance barrier [5,6,7,8]. Lots of attempts to reduce the pain have been reported in the literature by changing the design of tenaculum [9] or by applying anesthetics, all without success [5,10]. The grasping quality or the waiting time until the anesthetic alleviates the pain are unacceptable.


  1. “The Public Costs of Births Resulting from Unintended Pregnancies: National and State-Level Estimates.”, Sonfield, Adam, Kathryn Kost, Rachel B. Gold, and Lawrence B. Finer, Perspective on Sexual and Reproductive Health 43.2 (2011): 94-102
  2. “Contraceptive failure in the United States”, Trussell J., Contraception 2011;83:397–404
  3. “Effectiveness of long-acting reversible contraception”, Winner B, Peipert JF, Zhao Q, Buckel C, Madden T, Allsworth JE, Secura GMN Engl J Med. 2012 May 24; 366(21):1998-2007.
  4. “Cost Effectiveness of Contraceptives in the United States”, James Trussell, & all., Contraception. 2009 Jan; 79(1): 5–14
  5. “Interventions for pain with intrauterine device insertion”, Cochrane Database Syst Rev. 2015 Jul 29; (7) CD007373, Lopez LM, Bernholc A, Zeng Y, Allen RH, Bartz D, O’Brien PA, Hubacher D.
  6. “Practical advice for avoidance of pain associated with insertion of intrauterine contraceptives”, Luis Bahamondes, Diana Mansour, Christian Fiala, Andrew M Kaunitz, Kristina Gemzell-Danielsson, J Fam Plann Reprod Health Care 2014;40:54–60.
  7. “Use of the levonorgestrel releasing-intrauterine system in nulliparous women – a non-interventional study in Sweden”, Marions L, Lövkvist L, Taube A, et al. , Eur J Contracept Reprod Health Care2011;16:126–134
  8. “Cervical priming with misoprostol prior to transcervical procedures”, Fiala C, Gemzell-Danielsson K, Tang OS, et al., Int J Gynaecol Obstet 2007;99(Suppl. 2):S168–S171
  9. “Effect of an atraumatic vulsellum versus a single-tooth tenaculum on pain perception during intrauterine device insertion: a randomized controlled trial”, Nora Doty, Laura MacIsaac, Contraception 92 (2015) 567–571.
  10. “Prophylactic ibuprofen does not improve pain with IUD insertion: a randomized trial”, Paula H. Bednareka, Mitchell D. Creininb, Matthew F. Reevesc, Carrie Cwiakd, Eve Espeye, Jeffrey T. Jensena, Contraception 91 (2015) 193–197.